Introduction

Food allergy is an immune system response that develops shortly after consuming a specific food. Even a trace amount of the allergy-causing food might cause symptoms such as stomach issues, rashes, or inflamed airways. A food allergy can induce severe symptoms or even a life-threatening reaction known as anaphylaxis in certain people. Food allergies affect an estimated 8% of children under the age of 5 and up to 4% of adults. While there is no treatment for food allergies, some children outgrow them as they grow older. It’s easy to confuse a food allergy with food intolerance, which is a considerably more frequent reaction. Food intolerance, while annoying, is a less dangerous ailment that does not affect the immune system.

Peanut allergy

Peanut allergies afflict around 1 million children in the United States alone, and only one in every five of these children will outgrow their allergy. Because there is no treatment, allergic persons must avoid exposure at all costs in order to avoid severe and sometimes life-threatening responses. Peanut allergy is a disorder in which the body’s immune system incorrectly perceives even trace quantities of peanut as hazardous. Peanut allergies are variable in their prevalence and appearance, with some people having severe responses to even minimal quantities. Skin reactions (e.g., hives, redness, or swelling), stomach discomfort, or more serious reactions, such as constriction of the throat and airways and lack of appropriate blood supply to essential organs, can occur within seconds of contact. Antihistamines and epinephrine can be used to treat allergic responses, but even with timely treatment, severe reactions can be deadly.

Use of FDA approved new treatment for peanut allergy

Thousands of children and teenagers will benefit from a ground-breaking therapy for peanut allergy, The Palforzia medication helps to minimize the severity of allergic responses to peanuts, including anaphylaxis, making family vacations abroad, birthday celebrations, and Christmas goodies feasible for some children for the first time. Patients are given a monthly dosage, enabling for gradual tolerance development.

Palforzia dosage and steps
Palforzia treatment is divided into three stages: initial dose escalation, up-dosing, and maintenance. The Initial Dose Escalation phase is completed in one day. The Up-Dosing phase lasts many months and consists of 11 rising dosage levels. The initial dosage escalation, as well as the first dose of each Up-Dosing level, are provided under the supervision of a healthcare practitioner in a hospital facility capable of managing potentially severe allergic responses, such as anaphylaxis. While anaphylaxis can occur at any moment during Palforzia treatment, individuals are more vulnerable during and after the Initial Dosage Escalation and the first dose of each Up-Dosing level. Palforzia is a powder derived from peanuts that comes in pull-apart color-coded capsules for Dosing escalation and Up-dosing.
A randomized, double-blind, placebo-controlled trial of 500 peanut-allergic people in the United States, Canada, and Europe backs up Palforzia’s efficacy. After 6 months of maintenance medication, the proportion of trial participants who tolerated an oral challenge with a single 600 mg dose of peanut protein (double the daily maintenance dose of Palforzia) with no more than moderate allergy reactions was calculated.

Conclusively

Genetically inherited allergies have no cure, although advancements in technology and medicine had made it possible to develop so degree of tolerance to an allergens but it can’t be completely cured hence it is imperative to aslo adapt life styles changes to lead a normal and healthy life.

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