Owl’s eye appearance as shown on histopathology

Owl’s eye appearance is a pattern in radiology and histopathology. It is seen in:


  • Herpes Viruses Family infection as inclusion bodies, which are more commonly associated with cytomegalovirus.
  • Hodgkin’s lymphoma as Reed-Sternberg cells
  • Giardia lamblia trophozoites on microscopy.
  • Anitschkow cell of Aschoff bodies in rheumatic heart disease on transverse sections


  • CT scan of Cerebral hypoxia patients in Lentiform nucleus of the basal ganglia.
Cite this article as:
Burhan Ahmed, MD, "Owl’s Eye Appearance," in Medicalopedia, September 6, 2012, [Permalink: https://www.medicalopedia.org/3153/owls-eye-appearance/].